Guy Kawasaki has a solid post on his five top lessons for entrepreneurs: 1. Focus on Cash Flow 2. Make a little progress everyday 3. Try Stuff (serendipity is a part of success) 4. Ignore Schmexperts 5. Never Ask anyone to do something you wouldn't do A lot of times the workload and uncertainty can be daunting in a startup.  If you can't handle 5 I'll boil it down to the top 2: watch your cash and make a little progress everyday.